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Haplotypes
A haplotype is a set of closely linked genetic markers inherited as a unit. Each
person is a mosaic of their mother and father resulting from a blending of the DNA
they receive from each. All children, both sons and daughters, will carry identical
mitochondrial DNA from their mother, including any minor mutations or
polymorphisms. These polymorphisms are the basis for a person’s haplotype and
are unique and distinguishing from those of other individuals. Scientists have
determined approximately how often certain kinds of mutations occur and can look
for these and determine how closely related any two people are. The more
polymorphisms two people share, the more recently they had a common
ancestor. Genetic analysis of the mitochondrial DNA can reveal relationships
between different groups of people. The Haplotype Test can help locate recent
relatives from a single generation up to 25 generations or more, representing a
time frame from 0 to approximately 600 years.
Mito-Family™
Chromosomal Laboratories’ Mito-Family™ harnesses the power of mitochondria DNA to locate
maternally related people throughout the world. From a simple cheek swab, the laboratory analyzes
specific regions of DNA within the mitochondrial genome. The resulting DNA profile is researched in a
number of public mitochondrial DNA databases for possible genetic matches.
The Female Lineage – Mitochondrial DNA
The mitochondria is extraordinarily useful in tracing female genetic lineages. While mitochondrial DNA is
found in both males and females it is only passed from generation to generation by females. As a
consequence of this inheritance mechanism, it becomes an extremely powerful tool for genetic genealogy
and ancestry.